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= constitutive, green = smooth muscle-specific, yellow = striated
muscle-specific, and white = variable)
are indicated with their encoded amino acids (numbered). Experimentally
documented splicing pathways (solid lines) and others (dotted
lines) inferred from nuclease protection mapping are shown. The
smooth and striated exons encoding amino acids 39-80 are mutually
exclusive, and there are alternate 3'-terminal exons as well.
UT signifies untranslated regions.
Adapted from R. E. Breithart et al., Annu. Rev. Biochem. (1987) 56:467-495. © 1987 Annual Reviews.