URSA Engage Program 2013
Position Descriptions for Students to Apply For


Faculty Name & Department/School: Dr. Ryan A. Mehl, Department of Biochemistry and Biophysics. College of Science.


Research Project Title: Engineering Protein-Polymer Hybrids


Project Overview: 

All living organisms on the planet use the same 20 amino acids and the same basic 20 sets of translational components to incorporate those amino acids via the ribosome. Our lab has added additional sets of translational machinery to living organism expanding them past 20 amino acids. The new amino acids allows use to add or grow polymers from any protein. This protein polymer hybrid is a fundamental new matter that can them be used to interface the living and non-living worlds.


What skills will students obtain in this project? 

Protein expression and protein purification

Site-directed mutagenesis (PCR, DNA purification, DNA sequencing),

Synthesis of protein polymer hybrids and characterization.

Student research tasks: 



Period of work - Spring and Fall

Express unnatural proteins, construct protein polymer hybrids, purify and characterize protein polymer hybrids.

Number of hours per week expected of student:   10 


Preferred Faculty Contact Information: Ryan.mehl@oregonstate.edu

(note - applications are NOT sent to mentors - see instructions)

q Yes    x  No:   Human Subjects 

q Yes    x  No:   Live Vertebrate Animals

q Yes    x  No:   Recombinant DNA Molecules Transgenic Plants or Animal, and/or Infectious Agents of Plants, Animals, or Humans

q Yes    x  No:   Ionizing Radiation

q Yes    x  No:   Chemical Carcinogens

q Yes    x  No:   Scuba Diving, Free Diving

q Yes    x  No:   Small Boating Operations

If you are interested in applying for this position, you MUST complete the student application HERE and email it to Dr. Kevin Ahern at ahernk@onid.orst.edu

Do NOT email your application to the faculty mentor.