Biosynthetic Gene Cluster for

The Peptide Antibiotic Enduracidin

 

 

Reference ID: OSU-06-38

Inventors: Dr. Mark Zabriske, Dr. Xihou Yin

Description:  A variety of methods can be used to genetically manipulate the nucleic acid sequence encoding the enduracidin biosynthetic gene cluster in order to alter enduracidin production.

 This invention describes the molecular cloning of the enduracidin biosynthetic gene cluster from Steptomyces fungidicus and the characterization of the individual genes in the gene cluster and the proteins encoded. Biosynthetic gene clusters facilitate a molecular genetics approach to generate novel peptides.

 

Applications: Enduracidins analogs with improved biological and pharmacological properties

have been broadly used as animal food additives in Japan, China and other countries of Eastern Asia

License Terms: Exclusive or non-exclusive

Patent Status: US patent pending

For more information, contact:  

Mitra Kiani, Licensing Associate
Technology Transfer Office
Oregon State University
308 Kerr Administration Building
Corvallis, Oregon 97331-2140, USA

E-mail: Mitra.Kiani@oregonstate.edu

Telephone: (541) 737-3030
Facsimile: (541) 737-3093