A new study suggests that some children may be genetically predisposed to developing behavioral problems in child care and preschool settings.
BEND, Ore. – A new study suggests that some children may be genetically predisposed to developing behavioral problems in child care and preschool settings.
Previous research has found that some children develop behavior problems at child care centers and preschools, despite the benefit of academic gains. It was never known, however, why some youngsters struggle in these settings and others flourish. The new study indicates that some children may be acting out due to poor self-control and temperament problems that they inherited from their parents.
The study’s lead author Shannon Lipscomb, an assistant professor of human development and family sciences at Oregon State University-Cascades, said the findings point to the reason that some children develop problem behavior at care centers, despite the best efforts of teachers and caregivers. The results are published online today in the International Journal of Behavioral Development.
“Assuming that findings like this are replicated, we can stop worrying so much that all children will develop behavior problems at center-based care facilities, because it has been a concern,” she said. “But some children (with this genetic predisposition) may be better able to manage their behavior in a different setting, in a home or smaller group size.”
Researchers from Oregon State University and other institutions collected data in 10 states from 233 families linked through adoption and obtained genetic data from birth parents as well as the children. They found that birth parents who had high rates of negative emotion and self-control, based on a self-reported temperament scale, were more likely to have children who struggled with behavioral issues such as lack of self-control and anger, in child care centers. They controlled for adoptive parent’s characteristics, and still found a modest effect based on the genetic link.
“We aren’t recommending that children are genetically tested, but parents and caregivers can assess a child’s needs and help them get to a setting that might be more appropriate,” Lipscomb said. “This study helps us to explain why some children struggle so much with large peer groups and heightened social interactions. It may not be a problem with a teacher or parent, but that they are struggling on a biological level.”`
Lipscomb is in OSU’s College of Public Health and Human Sciences. She is an expert on early childhood development and school readiness, and is particularly interested in adult influences on young children.
Researchers from the University of Oregon, Pennsylvania State University, University of Pittsburgh, University of California, Riverside, Yale Child Study Center, and Oregon Social Learning Center contributed to this study, which was supported by grants from the National Institutes of Health.OSU-Cascades Campus Media Contact: Angela Yeager Source:
Shannon Lipscomb, 541-322-3137
Oregon State University and the Oregon Health Authority have received $1.25 million from the Centers for Disease Control to study the health impact of opening the Oregon Health Plan to more people.
CORVALLIS, Ore. – Oregon State University and the Oregon Health Authority have received $1.25 million from the Centers for Disease Control to study the health impact of opening the Oregon Health Plan to more people.
The five-year study will evaluate how the health of low-income women and their infants is affected when more of them are eligible for Medicaid health care coverage, i.e., the Oregon Health Plan. According to researchers, this study’s results will inform health reform efforts in Oregon and across the nation, as many states and communities undergo sweeping changes under the Affordable Care Act.
The OSU team will be led by researchers in the College of Public Health and Human Sciences, including Marie Harvey, Jeff Luck, Jocelyn Warren and Jangho Yoon.
“Oregon is an ideal state to conduct this study because of its ongoing commitment to Medicaid health care delivery for all, and the commitment of state leaders to collaborate to ensure this program’s success,” said Harvey, associate dean for research in OSU’s College of Public Health and Human Sciences, and one of the grant’s principal investigators.
One of the study’s goals will be to create an integrated, state-level data system that links de-identified Medicaid information with other existing health care data, such as from hospitals and birth and death certificates. This data system will help answer critical questions about the effect of Medicaid expansion on the use of health services and health outcomes among women and their children. A diverse group of county and community groups in the state with interest in maternal and child health will participate in setting research priorities for the study.
The project has been endorsed by Gov. John Kitzhaber, who has led the state’s efforts on implementation of comprehensive reform of Oregon’s Medicaid financing and delivery system. The research will also be helpful as Oregon looks towards the adoption of a more coordinated care model across all types of health care delivery systems.
“This project is an ideal complement to ongoing health system innovation and reforms in Oregon,” said Mike Bonetto, senior health care policy adviser to Gov. Kitzhaber. “This project will play a key role in our action plan by providing concrete data on how we can improve the health care and health outcomes of Medicaid-eligible women and their infants, a particularly vulnerable population.”College of Public Health and Human Sciences Media Contact: Angela Yeager Source:
Marie Harvey, 541-737-3824
CORVALLIS, Ore. – As a linebacker for the Chicago Bears, Dick Butkus developed a reputation as one of the toughest, most intense players the National Football League had ever seen.
In a story written by Larry Schwartz for ESPN.com, former Green Bay running back MacArthur Lane spoke of the Butkus intimidation factor: “If I had a choice,” he said, “I’d sooner go one-on-one with a grizzly bear. I prayed that I could get up every time Butkus hit me.”
Want to know what makes the Football Hall-of-Fame Dick Butkus tick? You’ll have a chance to ask him a question – about anything.
Butkus will speak at Oregon State University on Friday, Nov. 1, beginning at 12:30 p.m. in LaSells Stewart Center (located at 26th Street and Western Boulevard in Corvallis). His free, public presentation, which is sponsored by University Relations and Marketing at OSU, is appropriately titled, “Ask Me Anything.”
The event is free and open to the public, and people may submit questions in advance at: http://bit.ly/H0fnmv
There’s a pretty good chance he won’t even tackle you. While intimidating on the gridiron, Butkus is known as an engaging speaker who has channeled his tenacity into a new cause – fighting against steroid abuse in high school sports. He is the founder of the “I Play Clean” campaign.
Butkus was a two-time All-American at the University of Illinois, where he played center on offense and linebacker on defense. As a Chicago Bear, he was named to the All-NFL team seven times and played in the Pro Bowl eight times before his career was cut short by knee injuries.
For the past 29 years, top linebackers around the country have been honored with the Butkus Award, second only to the Heisman Trophy in name recognition, which is given at the high school, college and professional levels.
Later in the day, Butkus will attend the OSU football game against the USC Trojans, which begins at 6 p.m. in Reser StadiumGeneric OSU Media Contact: Mark Floyd Source:
Shelly Signs, 541-737-0724; email@example.com
CORVALLIS, Ore. - Darrin Crescenzi, a 2007 Oregon State University design graduate named by Fast Company magazine as one of the 100 most creative people in business, will return to OSU this weekend for a free presentation Friday on how “design thinking” opens the door to a wide variety of fields.
The former Nike designer gained notice for an array of work including the initials-and-crown personal logo of NBA superstar LeBron James, the uniforms worn by the American men’s Olympic basketball team in London in 2012, and a wildly popular poster he produced of the sigils (family seals) for the fictional Houses of Westeros in the book and TV hit “Game of Thrones.”
Crescenzi graduated from high school in tiny Gilchrist, Ore., in a class of 14, and is now senior designer in the Manhattan offices of Prophet, a worldwide brand and marketing firm. Joining him in the presentation will be his longtime partner Erin Mintun, also a former Nike designer and a 2007 OSU design graduate. She has special expertise in the role of color in consumer choices, and now works as a style forecaster for companies that must anticipate fashion trends.
Both will show examples of their work. The two designers were featured in the most recent issue of the OSU alumni magazine, the Oregon Stater. That story is available at http://j.mp/crescenzi.
The free public presentation, sponsored by the School of Design and Human Environment in OSU’s College of Business, will run from noon until 1 p.m. on Friday, Oct. 25, in the Willamette Room of the CH2M HILL Alumni Center, which is across 26th Street from Reser Stadium. Crescenzi will be in town to accept the OSU Alumni Association’s Young Alumni Award at a ceremony that night at the alumni center, where he will be joined by six fellow alumni who will be honored as OSUAA Alumni Fellows.
The alumni fellow honorees include:
- The Honorable Jack R. Borsting, College of Science;
- Martin Goebel, College of Forestry.
- Sandra Henderson, College of Science;
- Debra Nelson, College of Veterinary Medicine;
- Carol Hill Pickard, College of Home Economics;
- James E. Womack, College of Agricultural Sciences.
Reservations are required to attend the awards gala, which starts at 6 p.m. For more information on this and other Homecoming events, visit www.osualum.com/homecoming.Alumni Association Media Contact: Kevin Miller Source:
Kate Sanders, 541-737-6220Multimedia Downloads Multimedia:
Erin Mintun and
Two long-time journalists give a detailed account of the rich history of newspapers in the Northwest in a new book just published by Ridenbaugh Press.
CORVALLIS, Ore. – Two long-time journalists give a detailed account of the rich history of newspapers in the Northwest in a new book just published by Ridenbaugh Press.
"New Editions: The Northwest's Newspapers as They Were, Are, and Will Be" by Steve Bagwell, managing editor of the McMinnville-based News-Register, and Randy Stapilus, former Idaho reporter, examines the newspaper business in Idaho, Oregon, and Washington. Bagwell has taught media classes at Oregon State University since 1998.
Print newspapers nationally face an uncertain future as readers increasingly turn to the Internet for their daily news fix. Major changes are in the pipeline at most of the major dailies.
The book by Bagwell and Stapilus reviews every newspaper produced in Idaho, Oregon, and Washington – and there are a lot more than most people might think – covering the papers’ predecessors and evolution into their current form.
“New Editions” traces individual papers' transformation from locally, often family-owned publications to the ownership consolidation of larger groups, and the reasoning behind publishers' and editors' decisions on whether to produce online editions. Many of the region's editors and publishers offer their own comments and observations on the present and future of Northwest newspapers.
“New Editions: The Northwest’s Newspapers as They Were, Are and Will Be,” is available at bookstores and online at http://www.ridenbaugh.com/index.php/ridenbaugh-book-store/new-editionsCollege of Liberal Arts Media Contact: Angela Yeager Source:
Steve Bagwell, 503-437-5980
CORVALLIS, Ore. – On your next hike, instead of puzzling over the name of that large upright shrub with tiny white flowers and small red fruits, reach for the new field guide "Shrubs to Know in Pacific Northwest Forests" to quickly identify it as the native red elderberry.
Ed Jensen, a professor in Oregon State University's College of Forestry, authored the full-color, easy-to-use field guide for the OSU Extension Service.
The soft-cover, glossy book, available at http://bit.ly/OSU_ShrubstoKnow, describes nearly 100 different shrubs native to Pacific Northwest forests. It is useful to hikers and plant enthusiasts in Oregon, Washington, northern California, southern British Columbia, the panhandle of Idaho and adjoining parts of western Montana. It features 500 color photographs, an illustrated glossary of shrub terms, individual range maps and complete descriptions for each shrub species. It took Jensen about five years to research, write and photograph all the shrubs for the guide, which was published and designed by OSU's Extension and Experiment Station Communications department.
The new guide is a companion to his popular "Trees to Know in Oregon" book, originally authored in 1950 by former OSU Extension forester Charles R. Ross. Under Jensen's authorship, "Trees to Know" has undergone several major enhancements and revisions, including the addition of color photos in 2005 and the publication of a 60th anniversary edition in 2010. It has always been one of the most requested publications in the OSU Extension catalog.
"I meet people from all around the state who tell me that 'Trees to Know' helped launch their interest in Oregon's trees and forests," Jensen said. "I think it helps people develop a relationship with the forest when they get to know individual trees. I hope 'Shrubs to Know' will have that same impact."
Jensen teaches courses on tree and shrub identification and runs natural resource education programs at OSU. For about 10 years he served as director of two large continuing education programs for field-based natural resource specialists – the Silviculture Institute and the Natural Resources Institute.
You can meet Jensen at two upcoming public book signings set for 11 a.m. to 5 p.m. Nov. 22 at the Holiday Craft Fair at the West Linn Lutheran Church and 10 a.m. to 2 p.m. Dec. 7 at the Authors and Artists Fair at the Lane County Fairgrounds in Eugene.
The book costs $12, plus shipping and handling, and may be ordered from the OSU Extension catalog at http://bit.ly/OSU_ShrubstoKnow or by calling 1-800-561-6719.Extension Service Media Contact: Denise Ruttan Source:
Ed Jensen, 541-737-2519Multimedia Downloads Multimedia:
"Shrubs to Know in Pacific Northwest Forests" is a new field guide published by the Oregon State University Extension Service and authored by Ed Jensen, a professor in Oregon State University's College of Forestry. (Photo by OSU's EESC.)
Getting a wireless unmanned kiosk at Hatfield took the help of several state agencies.
NEWPORT, Ore. – The Visitor’s Center at Oregon State University’s Hatfield Marine Science Center was facing a serious problem. Donations were dropping, and staff members were trying to figure out why.
Then they hit on a realization. The donation box accepted cash, but very few people carry cash any more. The simple solution was to install a kiosk in the lobby that accepted donations via debit and credit cards.
But that’s when things got complicated. Because of security issues, as a governmental entity, the center wasn’t allowed to operate a wireless payment kiosk. The same issue prevented state workers such as Extension agents from using wireless card swipers when selling items at county fairs.
It all comes down to something called PCI (payment card industry) compliance. These national standards ensure the safety of debit and credit transactions, but to be in legal compliance as a state or governmental agency can be tricky. So Oregon Sea Grant’s Mark Farley, who works at the Hatfield Center, reached out to OSU’s Dee Wendler with the University Administration Business Center on campus, to find out how they could work with the State of Oregon to make compliance possible.
Wendler did some research, and was able to identify a company offering web-based PCI compliant payment services that was already under contract with the State of Oregon. However, recent changes to Oregon laws prevented OSU from utilizing the State’s contract, and prevented the Department of Justice from providing public universities advice or a review of the legal details surrounding the installation of an unmanned kiosk.
That’s when Wallace Rogers, State of Oregon manager of e-Government and Voice Services, stepped in. “It took some thinking outside the box,” Rogers said.
Rogers’ office contracts with an e-Government company, NIC-USA, to provide $1.8 billion in state e-commerce each year, and by contracting with them, Hatfield was able to be PCI compliant without taking on additional risk. Rogers’ office was able to contract with the Department of Justice to do a legal sufficiency review of the proposed Hatfield project.
Working with NIC not only allows Hatfield to install a cellular, wireless, unmanned kiosk (which should be installed by January) but may also open up the opportunity for OSU Extension agents and others who have items for sale to do so at a variety of locations outside of their offices.
“To have the ability to use a card swipe service will increase the efficiency of OSU employees, and increase their ability to do outreach,” Wendler said.
OSU’s Farley is grateful that so many entities came together to help solve what ended up being a rather complicated problem.
“Both the Justice Department and the Treasury Department went out of their way to help us negotiate the process,” Farley said.
Wendler believes if the kiosk is successful, it could be a model for other Oregon universities and state agencies.Hatfield Marine Science Center Media Contact: Theresa Hogue Source:
Mark Farley, 541-867-0276
Dee Wendler, 541-737-4128
CORVALLIS, Ore. – The Oregon State University football team will be showcased in a national prime time game against the University of Southern California in OSU’s Reser Stadium beginning at 6 p.m. on Nov. 1, a rare Friday night game that will bring attention – and a logistical challenge – to the campus.
“We are expecting many of our local and out-of-town fans to come to Corvallis early for the game, which will place some unprecedented demands on parking,” said Steve Clark, OSU’s vice president for University Relations and Marketing. “In anticipation of the game, the university has worked to create a ‘phased-in’ parking schedule to better coordinate activities.”
“The goal is to welcome the visitors, yet reduce the impact on OSU students and employees to the greatest extent possible,” Clark added.
The Department of Intercollegiate Athletics and the office of Transit and Parking Services will begin implementing the plan on Oct. 31, when some of the first recreational vehicle (RV) patrons arrive.
Beginning at 7 a.m. on Friday, Nov. 1, some parking lots will be open only to those with athletics-issued game-day parking passes. These include:
- All Reser Stadium parking lots;
- The parking garage at 26th Street and Washington Way (except for the fifth level, which will remain available for resident student parking);
- The gravel parking lot behind the Softball Complex and the Hilton Garden Inn;
- South Farm parking lot off Brooklane Road.
Other parking areas (listed below) will be available until 1 p.m. for regular faculty/staff business day parking. After 1 p.m., however, entrance to these areas will be limited only to people with athletics-issued game-day parking permits. Employee and student vehicles already parked in these lots may remain until 5 p.m., at which time all vehicles without athletics-issued passes must vacate. Signs will be posted at the entrance of these lots. These include:
- Lots between 15th Street and 11th Street, off Washington Way;
- The Benton Place parking lots east of Goss Stadium;
- Lots off Washington Way adjacent to the Student Legacy Park (intramural fields);
- The 30th Street parking lots around Peavy Hall, between Jefferson Street and Washington Way;
- The 30th Street parking lot by Magruder Hall;
- The 35th Street parking lot at the OSU Foundation building;
- The lot off 15th Street and Western Boulevard at the University Plaza building;
- For RVs: The gravel parking lot at 30th Street and Campus Way next to the Motor Pool.
All other Faculty/Staff parking lots that are designated as “Athletics Event” parking on game days are available for regular business-day parking, OSU officials say. However, employees are encouraged to vacate these lots by 5 p.m.
RV’s are only allowed after 5 p.m. on Thursday, Oct. 31, in the gravel lot off 35th and Campus Way, next to the Motor Pool. Employees and students who normally park in this location, should give themselves extra time Friday morning to locate a parking space as many may be filled with recreational vehicles. RV’s are not permitted on campus in any other lot.
A map is available to help visitors, students and employees better understand designated lots. It is available online at: http://www.flickr.com/photos/oregonstateuniversity/10275103273/
“We realize that despite our best efforts and intentions, some students and employees may be inconvenienced,” Clark said. “Everyone’s cooperation and understanding is appreciated.”
The Corvallis Transit System map is accessible at: http://www.corvallisoregon.gov/index.aspx?page=884Generic OSU Media Contact: Mark Floyd Source:
Steve Clark, 541-737-3808 (cell: 503-502-8217)
A new study concludes that by 2100, about 98 percent of the world's oceans will be affected by acidification, warming temperatures, low oxygen, or lack of biological productivity.
CORVALLIS, Ore. – A new study looking at the impacts of climate change on the world’s ocean systems concludes that by the year 2100, about 98 percent of the oceans will be affected by acidification, warming temperatures, low oxygen, or lack of biological productivity – and most areas will be stricken by a multitude of these stressors.
These biogeochemical changes triggered by human-generated greenhouse gas emissions will not only affect marine habitats and organisms, the researchers say, but will often co-occur in areas that are heavily used by humans.
Results of the study are being published this week in the journal PLoS Biology. It was funding by the Norwegian Research Council and Foundation through its support of the International Network for Scientific investigation of deep-sea ecosystems (INDEEP).
“While we estimated that 2 billion people would be impacted by these changes, the most troubling aspect of our results was that we found that many of the environmental stressors will co-occur in areas inhabited by people who can least afford it,” said Andrew Thurber, an Oregon State University oceanographer and co-author on the study.
“If we look on a global scale, between 400 million and 800 million people are both dependent on the ocean for their livelihood and also make less than $4,000 annually,” Thurber pointed out. “Adapting to climate change is a costly endeavor, whether it is retooling a fishing fleet to target a changing fish stock, or moving to a new area or occupation.”
The researchers say the effect on oceans will also create a burden in higher income areas, though “it is a much larger problem for people who simply do not have the financial resources to adapt.”
“What is really sobering about these findings is that they don’t even include other impacts to the world’s oceans such as sea level rise, pollution, over-fishing, and increasing storm intensity and frequency,” added Thurber, a post-doctoral fellow in OSU’s College of Earth, Ocean, and Atmospheric Sciences. “All of these could compound the problem significantly.”
In their study, the researchers used global distribution maps of 32 marine habitats and biodiversity hotspots and overlaid that with climate models developed for the Intergovernmental Panel on Climate Change Fifth Assessment Report, presented in Stockholm, Sweden, this fall. They then compared the results with the latest available data on human use of marine goods and services to estimate the vulnerability of coastal populations worldwide.
The models had a range of outcomes, but all agreed that most of the world’s oceans would suffer negative impacts of varying intensities from the four major stressors. Only a small fraction of the oceans – mostly in Antarctica and to a lesser extent, small areas of the Atlantic – will see potential increases in oxygen or biological productivity, the study noted.
By 2100, nowhere in the world are ocean waters expected to be cooler or less acidic than they are today.
“When you look at overlapping stressors, the Northern Hemisphere appears to be in real trouble,” Thurber said. “The same grim outlook is apparent for the strong upwelling zones off Chile and southern Africa. Another ‘red spot’ is the Pacific Northwest of the United States, which already is seeing the impact of low oxygen and rising acidification.”
It is the combination of stressors that makes upwelling areas – where deep, nutrient-rich water is brought to the surface to fertilize the upper water column – of greatest concern, the researchers noted. The models also suggest that marine food webs based on the production of euphausiids and other krill, or tiny marine crustaceans, are highly at-risk.
“A lot of marine animals, including many whale populations, are dependent upon krill or the other organisms that consume krill, for survival – and krill habitat has some of the greatest overlap in all the stressors we looked at,” Thurber said. “On the other hand, coral reefs – even though they didn’t rank as high as other areas for stressor overlap – are in trouble due to just two of the stressors, acidification and temperature. So a low score doesn’t necessarily mean these areas are unlikely to be affected.”
Thurber and three colleagues originally conceived of the idea of the meta-analysis of data to forecast the impact of climate change on the world’s deep sea, an idea that was re-cast when they organized an international workshop that drew many principal investigators of recent climate change studies. Notable among the researchers was Camila Mora of the University of Hawai’i at Mañoa, who spearheaded an effort to include shallow water and the human elements into the data analysis.
“The consequences of these co-occurring changes are massive,” Mora said. “Everything from species survival to abundance, to range size, to body size, to species richness, to ecosystem functioning are affected by changes in ocean biogeochemistry.”
The study is unusual because of its scope, and the analysis of multiple factors. Most previous studies have looked at one variable – such as ocean warming or increasing acidification – but not multiple stressors, or they focused on one geographic area. It also brought the human dimension into play, which few climate change studies have attempted.
“One of the real highlights of the study is its inclusion of the deep sea into our understanding of human impacts on climate,” Thurber said. “We often think of this vast habitat as immune to human activity, but we found that this largest and most stable area of our planet is likely to see multiple impacts from our activities.”
Among the possible biological responses to the four stressors:
- Although warming off the surface waters in polar regions may lead to enhanced growth and productivity of some species, in a vast majority of the world it likely will lead to species loss, reduced animal density, and enhanced risk of disease;
- Acidification will increase mortality of calcifying marine invertebrates and likely lead to species loss;
- Hypoxia, or low oxygen, will cause mortality in many species and could enhance dominance by other species that are hypoxia-tolerant;
- As productivity declines, many food web structures will be altered and reduced abundance may lead to dominance shifts from large to small species.
Andrew Thurber, 541-737-8251; firstname.lastname@example.orgMultimedia Downloads Multimedia:
OSU engineers and pharmaceutical researchers have developed an innovative use of nanotechnology and chemotherapy to improve the treatment of ovarian cancer.
The study this story is based on is available online: http://bit.ly/18PLoY4
CORVALLIS, Ore. – The combination of heat, chemotherapeutic drugs and an innovative delivery system based on nanotechnology may significantly improve the treatment of ovarian cancer while reducing side effects from toxic drugs, researchers at Oregon State University report in a new study.
The findings, so far done only in a laboratory setting, show that this one-two punch of mild hyperthermia and chemotherapy can kill 95 percent of ovarian cancer cells, and scientists say they expect to improve on those results in continued research.
The work is important, they say, because ovarian cancer – one of the leading causes of cancer-related deaths in women – often develops resistance to chemotherapeutic drugs if it returns after an initial remission. It kills more than 150,000 women around the world every year.
“Ovarian cancer is rarely detected early, and because of that chemotherapy is often needed in addition to surgery,” said Oleh Taratula, an assistant professor in the OSU College of Pharmacy. “It’s essential for the chemotherapy to be as effective as possible the first time it’s used, and we believe this new approach should help with that.”
It’s known that elevated temperatures can help kill cancer cells, but heating just the cancer cells is problematic. The new system incorporates the use of iron oxide nanoparticles that can be coated with a cancer-killing drug and then heated once they are imbedded in the cancer cell.
Other features have also been developed to optimize the new system, in an unusual collaboration between engineers, material science experts and pharmaceutical researchers.
A peptide is used that helps guide the nanoparticle specifically to cancer cells, and the nanoparticle is just the right size – neither too big nor too small – so the immune system will not reject it. A special polyethylene glycol coating further adds to the “stealth” effect of the nanoparticles and keeps them from clumping up. And the interaction between the cancer drug and a polymer on the nanoparticles gets weaker in the acidic environment of cancer cells, aiding release of the drug at the right place.
“The hyperthermia, or heating of cells, is done by subjecting the magnetic nanoparticles to an oscillating, or alternating magnetic field,” said Pallavi Dhagat, an associate professor in the OSU School of Electrical Engineering and Computer Science, and co-author on the study. “The nanoparticles absorb energy from the oscillating field and heat up.”
The result, in laboratory tests with ovarian cancer cells, was that a modest dose of the chemotherapeutic drug, combined with heating the cells to about 104 degrees, killed almost all the cells and was far more effective than either the drug or heat treatment would have been by itself.
Doxorubicin, the cancer drug, by itself at the level used in these experiments would leave about 70 percent of the cancer cells alive. With the new approach, only 5 percent were still viable.
The work was published in the International Journal of Pharmaceutics, as a collaboration of researchers in the OSU College of Pharmacy, College of Engineering, and Ocean NanoTech of Springdale, Ark. It was supported by the Medical Research Foundation of Oregon, the PhRMA Foundation and the OSU College of Pharmacy.
“I’m very excited about this delivery system,” Taratula said. “Cancer is always difficult to treat, and this should allow us to use lower levels of the toxic chemotherapeutic drugs, minimize side effects and the development of drug resistance, and still improve the efficacy of the treatment. We’re not trying to kill the cell with heat, but using it to improve the function of the drug.”
Iron oxide particles had been used before in some medical treatments, researchers said, but not with the complete system developed at OSU. Animal tests, and ultimately human trials, will be necessary before the new system is available for use.
Drug delivery systems such as this may later be applied to other forms of cancer, such as prostate or pancreatic cancer, to help improve the efficacy of chemotherapy in those conditions, Taratula said.Generic OSU Media Contact: David Stauth Source:
Oleh Taratula, 541-737-5785Multimedia Downloads Multimedia:
CORVALLIS, Ore. – As the worldwide population of honey bees continues to decline, the Oregon State University Extension Service and partners have updated a tool for Pacific Northwest growers and beekeepers to reduce the impacts of pesticides on bees.
The revision of OSU Extension's publication appears after an estimated 50,000 bumble bees died in a Wilsonville parking lot in June. The Oregon Department of Agriculture confirmed in a June 21 statement that the bee deaths were directly related to a pesticide application on linden trees conducted to control aphids. The episode prompted the ODA to issue a six-month restriction on 18 insecticides containing the active ingredient dinotefuran.
OSU researchers are investigating the effects of broad-spectrum neonicotinoids, such as dinotefuran, on native bees. The work is in progress, according to Ramesh Sagili, an OSU honeybee specialist.
The newly revised publication "How to Reduce Bee Poisoning from Pesticides" includes the latest research and regulations. Lead authors include Sagili and OSU toxicologist Louisa Hooven. Download the updated version for free online at http://bit.ly/OSU_ReduceBeePoisoning.
"More than 60,000 honey bee colonies pollinate about 50 different crops in Oregon, including blueberries, cherries, pear, apple, clover, meadowfoam and carrot seed," Sagili said. "Without honey bees, you lose an industry worth nearly $500 million from sales of the crops they commercially pollinate."
Nationally, honey bees pollinated about $11.68 billion worth of crops in 2009, according to a 2010 study on the economic value of insect pollinators by Cornell University.
Growers, commercial beekeepers and pesticide applicators in Oregon, Washington, Idaho and California will find the publication useful, Sagili said. An expanded color-coded chart details active ingredients and trade names of more than 100 conventional and organic pesticides, including toxicity levels to bees and precautions for use.
The publication also describes residual toxicity periods for several pesticides that remain effective for extended periods after they are applied. Additionally, the guide explains how to investigate and report suspected bee poisonings.
Nationwide, honey bee colonies have been declining in recent years due to several factors, including mites, viruses transmitted by mites, malnutrition and improper use of pesticides, Sagili said. In Oregon, about 22 percent of commercial honey bee colonies were lost during the winter of 2012-13, Sagili said. There has been a gradual, sustained decline of managed honey bees since the peak of 5.9 million colonies in 1947, according to the Cornell study. The number of managed colonies reached a low of 2.3 million in 2008, although there were increases in 2009 and 2010, the study said.
"Growers and beekeepers can work together with this practical document in hand," Sagili said of OSU Extension's publication. "It gives them informative choices."
For example, when commercial beekeeper Harry Vanderpool needed to advise a pear grower on whether an insecticide was acceptable to use around bees, he turned to OSU Extension's publication.
"That manual has been a blessing," said Vanderpool, who keeps 400 hives in South Salem to pollinate dozens of crops for growers from California to central Oregon. "It's a tool that helps beekeepers and farmers work together in the right way with the right chemical rather than us telling farmers how to farm or farmers telling beekeepers how to keep bees."
You can also find OSU's publication by searching for PNW 591-E in OSU Extension's catalog at http://extension.oregonstate.edu/catalog. The publication was produced in cooperation with OSU, Washington State University and the University of Idaho.Extension Service Media Contact: Denise Ruttan Source:
PORTLAND, Ore. – Mark Abbott, dean of the College of Earth, Ocean, and Atmospheric Sciences at Oregon State University, will give the keynote speech at the Achievement Rewards for College Scientists (ARCS) Foundation scholars luncheon on Tuesday, Oct. 22, in Portland.
The event begins at 11 a.m. at the Portland Art Museum, where 52 ARCS scholars will be honored and present posters of their research. Ticket information is available online at: https://www.arcsfoundation.org/portland/news/portland-chapters-9th-annual-luncheon-celebrates-50-american-science-scholars
Abbott’s talk, “Our Oceans under Pressure,” will outline how human impacts on the world’s oceans are increasing, raising concern for such issues as declining fisheries, sea level rise, pollution, acidification, harmful algal blooms, and marine “dead zones.”
Abbott is president of the Oceanographic Society and a former member of the National Science Board. In 2011, he received the prestigious Jim Gray eScience Award in Stockholm, Sweden, from Microsoft Research for his leadership in blending science and computing technology. He joined the OSU faculty in 1988 and has served as dean of the college since 2001.
Julia Maxson of Oregon Health & Science University will be the featured ARCS Scholar Alumna speaker. Her talk is titled “Using Genetics to Find Better Cancer Treatments.”
Fifty-two scholars at OSU and OHSU will be honored at this ninth annual luncheon.College of Earth, Ocean, and Atmospheric Sciences Media Contact: Mark Floyd Source:
Jean Josephson, ARCS president, email@example.comMultimedia Downloads Multimedia:
Fisheries biologist Jim Lichatowich, an Oregon State alumnus, has written a new book on salmon management and recovery published by the OSU Press.
CORVALLIS, Ore. – For more than 40 years, Jim Lichatowich worked with Pacific salmon as a researcher, resource manager and scientific adviser, and he has seen first-hand the decline of Northwest salmon populations during that time.
In a new book published by the Oregon State University Press, Lichatowich outlines a plan for salmon recovery based on the lessons he has learned during his long career.
His book, “Salmon, People, and Place: A Biologist’s Search for Salmon Recovery,” points out many misconceptions about salmon that have hampered management and limited recovery programs. These programs will continue to fail, he argues, as long as they look at salmon as “products” and ignore their essential relationship with the environment.
Among his suggestions for reforming salmon management and recovery:
- Holding salmon managers and administrators accountable;
- Requiring agencies to do more “institutional learning”;
- Not relying on shifting baselines of data;
- Undertaking hatchery reform;
- Returning to place-based salmon management.
John Larison, author of “The Complete Steelheader,” praised the OSU Press book written by Lichatowich. “Part science, part anthropology, part philosophy, this is a revelatory book and essential reading for anyone hoping to understand salmon in the Northwest,” Larison said.
Lichatowich served for years on the Independent Scientific Advisory board for the Columbia River restoration program, as well as on Oregon’s Independent Multidisciplinary Science Team and other science groups in British Columbia and California. He is author of the award-winning book, “Salmon without Rivers: A History of the Pacific Salmon Crisis.”
In his newest book, Lichatowich writes: “We enthusiastically accepted the gift of salmon, but failed to treat it with the respect it deserves. We failed to meet our obligation to return the gift in the way that only humans can. We failed to return the gift of salmon with the gift of stewardship.”
Lichatowich is a graduate of OSU’s Department of Fisheries and Wildlife. He will return to his alma mater in January to present a seminar on his work.
“Salmon, People, and Place” is available in bookstores, online at http://osupress.oregonstate.edu, or can be ordered by calling 1-800-621-2736.College of Agricultural Sciences Media Contact: Mark Floyd Source:
Micki Reaman, 541-737-4620; Micki.firstname.lastname@example.orgMultimedia Downloads Multimedia:
Researchers have created a fundamentally different way to attack bacterial infection called a PPMO, which appears to function as well or better than an antibiotic.
CORVALLIS, Ore. – Researchers at Oregon State University and other institutions today announced the successful use of a new type of antibacterial agent called a PPMO, which appears to function as well or better than an antibiotic, but may be more precise and also solve problems with antibiotic resistance.
In animal studies, one form of PPMO showed significant control of two strains of Acinetobacter, a group of bacteria of global concern that has caused significant mortality among military personnel serving in Middle East combat.
The new PPMOs offer a fundamentally different attack on bacterial infection, researchers say.
They specifically target the underlying genes of a bacterium, whereas conventional antibiotics just disrupt its cellular function and often have broader, unwanted impacts. As they are further developed, PPMOs should offer a completely different and more precise approach to managing bacterial infection, or conceptually almost any disease that has an underlying genetic component.
The findings were published today in the Journal of Infectious Diseases, by researchers from OSU, the University of Texas Southwestern Medical Center, and Sarepta, Inc., a Corvallis, Ore., firm.
“The mechanism that PPMOs use to kill bacteria is revolutionary,” said Bruce Geller, a professor of microbiology in the OSU College of Science and lead author on the study. “They can be synthesized to target almost any gene, and in that way avoid the development of antibiotic resistance and the negative impacts sometimes associated with broad-spectrum antibiotics.
“Molecular medicine,” Geller said, “is the way of the future.”
PPMO stands for a peptide-conjugated phosphorodiamidate morpholino oligomer – a synthetic analog of DNA or RNA that has the ability to silence the expression of specific genes. Compared to conventional antibiotics, which are often found in nature, PPMOs are completely synthesized in the laboratory with a specific genetic target in mind.
In animal laboratory tests against A. baumannii, one of the most dangerous Acinetobacter strains, PPMOs were far more powerful than some conventional antibiotics like ampicillin, and comparable to the strongest antibiotics available today. They were also effective in cases where the bacteria were resistant to antibiotics.
PPMOs have not yet been tested in humans. However, their basic chemical structure, the PMO, has been extensively tested in humans and found safe. Although the addition of the peptide to the PPMO poses an uncertain risk of toxicity, the potency of PPMOs reduces the risk while greatly improving delivery of the PMOs into bacterial cells, Geller said.
Geller said research is being done with Acinetobacter in part because this pathogen has become a huge global problem, and is often spread in hospitals. It can cause respiratory infection, sepsis, and is a special concern to anyone whose immune system is compromised. Wounds in military battle conditions have led to numerous cases in veterans, and A. baumannii is now resistant to many antibiotics. “Urgent new approaches to therapeutics are needed,” the scientists said in their report.
Continued research and eventually human clinical trials will be required before the new compounds are available for health care, the researchers said. This and continued studies have been supported by the National Institutes of Health, the other collaborators and the N.L. Tartar fund.
Editor’s Note: A scanning electron microscope image of A. baumannii is available online (please provide image credit as indicated at web site): http://bit.ly/GztejRCollege of Science Media Contact: David Stauth Source:
Bruce Geller, 541-737-1845
Beaver BarCamp, hosted by the OSU Open Source Lab, will be held Saturday, Oct. 12, and allow participants to explore a wide range of topics.
CORVALLIS, Ore. – The 12th semiannual Beaver BarCamp, an informal conference where participants can explore anything from science to art, technology, food, art, culture or other topics, will be held Saturday, Oct. 12, at Oregon State University.
The event, which is hosted by the Open Source Lab at OSU, is free and open to the public. It will be at the Kelley Engineering Center on the OSU campus from 9 a.m. to 6:30 p.m., and will include presentations by the Corvallis Bicycle Collective, executive in residence Bob Mayes, and Open Source Lab director Lance Albertson.
Introductory science topics will be offered for high school students and interested community members, and participants can attend any portion of the day. A continental breakfast, lunch and afternoon snack will be provided.
Most sessions at Beaver BarCamp are not predetermined. It allows sharing of ideas and projects, discussions, demos and interaction among attendees, who both provide the sessions and choose the schedule. Anyone can participate in sessions throughout the day or propose their own, based on a project, hobby or research interest. More information is available online at http://beaverbarcamp.org
The Open Source Lab, which provides host and support services to more than 160 open source projects, will also have information sessions at Beaver BarCamp for those who are interested in learning more about the Open Source Lab and opportunities to become involved.College of Engineering Source: Melissa Morse
CORVALLIS, Ore. – Robin Kimmerer will read from her new book, “Braiding Sweetgrass: Indigenous Wisdom, Scientific Knowledge and the Teachings of Plants,” on Saturday, Oct. 19, beginning at 7:30 p.m. at Oregon State University’s LaSells Stewart Center, C&E Auditorium.
She’ll be joined by poet Alison Hawthorne Deming for an event celebrating the 10th anniversary of OSU Spring Creek Project’s Long-Term Ecological Reflections program. The program is free and open to all.
As a botanist and professor of plant ecology, Kimmerer has spent a career learning how to ask questions of nature using the tools of science. As a Potawatomi woman, she learned from elders, family, and history that the majority of indigenous cultures consider plants and animals to be the oldest teachers. In “Braiding Sweetgrass,” Kimmerer shows how other living things – asters and goldenrod, strawberries and squash, salamanders, algae, and sweetgrass – offer people gifts and lessons.
Jane Goodall said about “Braiding Sweetgrass,” “Robin Kimmerer has written an extraordinary book, showing how the factual, objective approach of science can be enriched by the ancient knowledge of the indigenous people.”
Kimmerer is a Distinguished Teaching Professor of Environmental Biology at the SUNY College of Environmental Science and Forestry and the founding director of the Center for Native Peoples and the Environment. Her first book, “Gathering Moss,” was awarded the prestigious John Burroughs Medal for Nature Writing.
Since its inception in 2003, Long-Term Ecological Reflections has hosted more than 40 writers-in-residence at the H. J. Andrews Experimental Forest, and sponsored field symposia on challenging topics such as “The Meaning of Watershed Health” and “New Metaphors for Restoration.”College of Liberal Arts Media Contact: Angela Yeager Source:
Charles Goodrich, 541-737-6198; Charles.email@example.com
Oregon State University has become a member institution of the Clinton Global Initiative University, an organization launched by President Bill Clinton to bring together student leaders from around the world.
CORVALLIS, Ore. – Oregon State University has become a member institution of the Clinton Global Initiative University, an organization launched by President Bill Clinton to bring together student leaders from around the world.
The program has five focus areas: education; environment and climate change; peace and human rights; poverty alleviation; and public health.
By becoming part of this network, OSU can send student leaders to the organization’s annual meeting, which includes student leaders and organizers, national and international experts, and some celebrities. The next meeting will be at Arizona State University in March, 2014.
Invited students develop “Commitments to Action,” which are new, specific and measurable initiatives that address challenges on their campus, in their community or on a larger national or global scale.
Laurie Bridges, assistant professor and librarian at OSU, worked closely with Vice Provost for Student Affairs Larry Roper to involve OSU in the CGI University Network. OSU’s emphasis on sustainability, entrepreneurship and social justice ties perfectly with the focus of the program, she said.
“I feel the CGI U is in perfect alignment with the mission and goals of our university,” Bridges said. “Promoting economic, social, cultural and environmental progress is part of OSU’s mission, which CGI University does on a global scale. Through the education they receive at OSU, our students are being prepared to be strong change agents in the world.”
OSU has committed $10,000 for students who participate in CGI University, part of which is offered as seed money for some of the initiatives they propose. The university will also provide support and mentoring to participating student leaders and entrepreneurs.
For more information see http://www.clintonglobalinitiative.orgGeneric OSU Media Contact: Theresa Hogue Source:
Researchers from OSU's Department of Fisheries and Wildlife are working with researchers in China to save one of the world's most endangered seabirds - the Chinese crested tern.
CORVALLIS, Ore. – A collaborative project between researchers in Asia and Oregon has helped establish a new breeding colony for one of the world’s most endangered seabirds – the Chinese crested tern, which has a global population estimated at no more than 50 birds.
Until this year, there were only two known breeding colonies for the critically endangered species (Thalasseus bernsteini) – both in island archipelagos close to the east coast of the People’s Republic of China. Once thought to be extinct, there were no recorded sightings of Chinese crested terns from the 1930s until 2000, when a few birds were rediscovered on the Matsu Islands.
This summer an innovative tern colony restoration began, with assistance from students and faculty in the Department of Fisheries and Wildlife at Oregon State University. Dan Roby, a professor of wildlife ecology at OSU, had previously led efforts to relocate populations of Caspian terns from locations along the Columbia River in Oregon, where the birds were consuming significant quantities of juvenile salmon.
“The problem was different in Oregon than it is in China, but the goal was the same – to alter the habitat in a good location in hopes of creating a breeding colony,” Roby said. “The methods also were similar and based on tern restoration techniques developed by Steve Kress of the National Audubon Society. You have to partially clear an island of vegetation, place decoys there, and attract birds using sound.”
In early May of 2013, an international team did just that on a small island in the Jiushan Islands called Tiedun Dao. Chinese crested terns used to breed on the archipelago a decade ago, increasing the chances that restoration could be successful there, Roby said.
The project team included members from the Xiangshan Ocean and Fishery Bureau, the Jiushan Islands National Nature Reserve, the Zhejiang Museum of Natural History, and OSU’s Department of Fisheries and Wildlife. The team members cleared brush off Tiedun Dao, place 300 tern decoys on the island, and used solar-powered playback systems to broadcast recorded vocalizations of both greater crested terns and Chinese crested terns.
“Greater crested terns are not endangered and when they establish colonies, it sometimes attracts the endangered Chinese crested tern,” Roby pointed out. “We thought if we could get them in to colonize the island, their numbers would eventually grow and the Chinese crested terns might follow.
“We just didn’t expect it to happen that quickly,” Roby added.
The researchers thought it might take years – but by July, a handful of greater crested terns were spotted flying over the decoys. By the end of that month, 2,600 greater crested terns had been documented and hundreds of pairs had laid eggs and begun incubating them. To the surprise of the restoration team, 19 adult Chinese crested terns were spotted on the island and at least two pairs laid eggs.
It was the highest single count of the endangered seabird in one location since the species’ rediscovery in 2000.
By late September – despite typhoons and a late start to the breeding season – more than 600 greater crested tern chicks, and at least one Chinese crested tern chick had successfully fledged.
Local officials say they are committed to the protection of the emerging colony.
“We will do our best to ensure good management of the Jiushan Islands National Nature Reserve and we also hope to receive more support for the conservation of the tern colony here in Xiangshan,” said Yu Mingquan, deputy director of the provincial Xiangshan Ocean and Fishery Bureau.
The success of the colony on Tiedun Dao is a “landmark for contemporary conservation in the region,” said Simba Chan, the senior Asia conservation officer for Birdlife. “No one dared imagine that the first year of such a challenging restoration project would be so successful.”
Funding for the project was provided by numerous sources internationally.College of Agricultural Sciences Media Contact: Mark Floyd Source:
Dan Roby, 541-737-1955; Daniel.Roby@oregonstate.eduMultimedia Downloads Multimedia:
Direct modification of DNA, or genetic engineering, is a tool for plant breeding that has spread at unprecedented speed over the last two decades. At the Oct. 14 Corvallis Science Pub, Steve Strauss, director of Oregon State University’s Outreach in Biotechnology program, will discuss the pros and cons of gene technology for agriculture.
CORVALLIS, Ore. – Direct modification of DNA, or genetic engineering, is a tool for plant breeding that has spread at unprecedented speed over the last two decades. At the Oct. 14 Corvallis Science Pub, Steve Strauss, director of Oregon State University’s Outreach in Biotechnology program, will discuss the pros and cons of gene technology for agriculture.
The Science Pub presentation begins at 6 p.m. in the Majestic Theater, at 115 S.W. Second St. in Corvallis. It is free and open to the public. In November, Science Pub will resume at its usual location at the Old World Deli.
Today’s agricultural bounty can be traced to traditional plant breeding and other technologies, but population growth and demands for higher quality food will require large improvements in agricultural productivity, said Strauss. The undesirable environmental and social effects of more intense farming systems also need to be minimized.
“Gene technology is a valuable tool, not a silver bullet,” Strauss added. “It can do a lot, but it must be used with due caution and as part of integrated, ecologically-guided management systems for sustained benefit.”
Biotechnology appears capable of providing major humanitarian benefits to the poor by improving nutrition and food security.
“Despite the fears and growing legal barriers, the stakes in this debate are too high to turn away from,” he said. “We must find socially acceptable ways to move forward.”
While genetic engineering can provide nutritional and agronomic benefits, it has also come up against strong social and legal resistance in many countries, making its future uncertain. Strauss will review what the technology actually is, how it is similar and different from conventional breeding, and how it has impacted agriculture to date. He will also discuss diverse sources of the controversy surrounding it, including the numerous myths and confusing science that pervade the online world.
Strauss is a distinguished professor in the Oregon State College of Forestry and a fellow of the Leopold Leadership Program at Stanford University. He is also the director of the Tree Biosafety and Genomics Research Cooperative at OSU that conducts research on mitigation of risks from genetic engineering in forestry.
-30-Generic OSU Media Contact: Nick Houtman Source:
Steve Strauss, 541-737-7568
Oregon State University is holding the fourth annual Be Well Walk & Run on Oct. 11
CORVALLIS, Ore. – Oregon State University is holding the fourth annual Be Well Walk & Run on Oct. 11 in the Memorial Union Quad. The event is free and open to everyone.
This year’s event includes a five-kilometer running course as well as a one-mile walking course (5k Map / 1-Mile Map). The scenic route will wind participants throughout OSU’s campus, highlighting picturesque buildings and spaces. Costumes are encouraged.
The event will feature activity stations in the Memorial Union Quad to engage participants in learning about the Healthy Campus Initiative, including physical activity, stress management, nutrition and a smoke-free campus.
Participants can register as individuals or as part of a group. Early registrants will receive a free 2013 Be Well Walk & Run t-shirt. To register, go to http://bit.ly/19Zo7Rk. The run starts at 3:30 p.m. in the quad, check in begins at 3 p.m.
For more information, go to http://oregonstate.edu/bewell
Accommodations for disabilities may be made by calling Joe Schaffer, 541-737-4884.Generic OSU Media Contact: Theresa Hogue Source:
Lisa Hoogesteger, 541-737-3343Multimedia Downloads Multimedia: