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an engineered DNA molecule used to clone DNA sequences in yeast cells. YACs are often used to map and sequence genomes. Segments of an organism's DNA, up to a million base pairs in length, can be inserted into YACs. These YACs can then taken up by yeast cells. As the cells grow and divide, they amplify the YAC DNA, which can be isolated and used for DNA mapping and sequencing. See also cloning vector |