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Figure N1

From: Holstege et al. (1998) Cell 95, 717-728. Model of RNA polymerase II transcription initiation machinery. The machinery depicted here encompasses over 85 polypeptides in complexes: core RNA polymerase III (RNAPII) consists of 12 subunits; TFIIH, 9 subunits; TFIIE, 2 subunits; TFIIF, 3 subunits; TFIIB, 1 subunit; TFIID, 14 subunits; core SRB/mediator, more than 16 subunits; Swi/Snf complex, 11 subunits; Srb10 kinase complex, 4 subunits; and SAGA, 13 subunits.