URSA Engage Program 2013
Position Descriptions for Students to Apply For


Faculty Name & Department/School:

Dr. Victor L. Hsu, Department of Biochemistry & Biophysics

Research Project Title:

Computational methods for predicting protein-protein interaction domains

Project Overview: 

The interaction between proteins is a vital part of essentially all life processes, and much effort has been spent in studying biomolecular interactions experimentally. However, the number of potential interactions is astronomical, so it would be useful if a computational approach could be developed to predict specific protein-protein interactions. This problem is two-fold: 1) which proteins interact?; and 2) what part of those proteins are responsible for the interaction? This project is directed towards the second question
and involves performing
in silico protein interaction simulations and statistical modeling and analysis. (Scripting skills would be useful.)

What skills will students obtain in this project? 

Accessing molecular structure databases
Setting up and running molecular simulations
Statistical methods for domain predictions

Student research tasks: 

Write computer scripts to facilitate workflow
Write computer scripts (and/or programs) to simplify database management
Perform protein-protein docking simulations

Period of work - Spring and Fall


Number of hours per week expected of student:     4-8


Preferred Faculty Contact Information:

By office visit (ALS 2143) or email (hsuv@onid.orst.edu)

(note - applications are NOT sent to mentors - see instructions)


q Yes    x No:   Human Subjects 

q Yes    xNo:   Live Vertebrate Animals

q Yes    x  No:   Recombinant DNA Molecules Transgenic Plants or Animal, and/or Infectious Agents of Plants, Animals, or Humans

q Yes    x  No:   Ionizing Radiation

q Yes    x  No:   Chemical Carcinogens

q Yes    x  No:   Scuba Diving, Free Diving

q Yes    x  No:   Small Boating Operations


If you are interested in applying for this position, you MUST complete the student application HERE and email it to Dr. Kevin Ahern at ahernk@onid.orst.edu

Do NOT email your application to the faculty mentor.