URSA Engage Program 2013
Position Descriptions for Students to Apply For


Faculty Name & Department/School: Dr. Claudia C. Häse, Department of Biomedical Sciences, College of Veterinary Medicine


Research Project Title: Chemotaxis behavior of Vibrio cholerae


Project Overview: 

Motile bacteria swim toward or away from certain chemicals or other favorable conditions by a directed movement known as chemotaxis. Vibrio cholerae, the causative agent of cholera, can swim by rotating its single polar flagellum as a screw propeller.  Upon ingestion, the organisms colonize the small intestine where they elaborate the potent cholera toxin that is directly responsible for the profuse diarrhea characteristic of the disease.  Bacteria are shed in large numbers in the diarrhea into the environment, where they can associate with other members of the ecosystem until they are ingested again, completing the life cycle of this organism.


What skills will students obtain in this project? 

Basic microbiological techniques, including sterile culture of the non-pathogenic Vibrio cholerae used in the research. PCR, molecular cloning, and the construction of gene knockouts will also be utilized.


Student research tasks: 

Culture bacteria, assess chemotaxis using measurement techniques. Construct gene knockouts in bacterial strains, and assess the resultant chemoatxis phenotype.  


Period of work - Spring ONLY


Number of hours per week expected of student:     10-12


Preferred Faculty Contact Information: hasec@science.oregonstate.edu

(note - applications are NOT sent to mentors - see instructions)

q Yes    q  No:   Human Subjects 

q Yes    q  No:   Live Vertebrate Animals

q Yes    q  No:   Recombinant DNA Molecules Transgenic Plants or Animal, and/or Infectious Agents of Plants, Animals, or Humans

q Yes    q  No:   Ionizing Radiation

q Yes    q  No:   Chemical Carcinogens

q Yes    q  No:   Scuba Diving, Free Diving

q Yes    q  No:   Small Boating Operations


Approval Number(s) from above, if relevant ___Proposal 1910________________

If you are interested in applying for this position, you MUST complete the student application HERE and email it to Dr. Kevin Ahern at ahernk@onid.orst.edu

Do NOT email your application to the faculty mentor.