Schedule time early each term to meet with an adviser.
Bring an updated copy of a degree audit, graduation checklist or transcript from a campus kiosk.
Prior to the meeting, ask yourself what your goals are (graduating on time, getting a certain kind of internship, holding a leadership position, being admitted to graduate school, etc.).
If you are uncertain about your goals, ask questions. Your adviser can tell you what kinds of internships are available, let you know about clubs and organizations that exist for your major, and give you insights on different ways to explore your field of study.
Review your schedule of classes or catalog before your appointment to give you an idea of what's being offered the next term.
Know your time limitations and be realistic in planning; take into account work schedules, athletic practice, campus involvements -- or maybe just the fact that you're not a morning person.
Do not expect an adviser to have all the answers. Do expect that your adviser will assist you in finding the resources or contacts needed to answer your questions.
Have fun getting to know your adviser!